First just try putting it in water and see if the pill dissolves on its own. A liquid preparation of an antidepressant or other psychiatric drug makes controlled tapering much easier. What I now do is place an elastic band around the barrel of the syr, -------------------------------------------------------------------------------------, ORIGINAL TOPIC: Making a Celexa Solution Yourself. So, what I'm doing now is taking 1/2 of my 40 mg (that gives me 20) and a 10mg pill (whhc she prescribed precisely for this), for a total of 30. Find answers to some commonly asked questions about amoxicillin. That term "biologically insignificant" used by a doctor is just plain wrong. Using fruit juice is also popular as a suspension media. A prolonged break in feeding is not required before/after administration. Before taking amoxicillin, be sure to tell your doctor about all medications you take (including prescription and over-the-counter kinds). As methanol is a highly polar solvent they generally produce polar compounds peak in gas chromatography. There are quite a few recipes available online using a variety of materials. My current dose is 5.25 mg of citalopram, so given the dilution I'm using (10 mg in 20 mL) I measure 10.5 mL as my daily dose. What is the shelf life of 500mg antibiotic capsual (cephalexin)? I'm not a doctor. I capped the bottle tightly and put it in the refrigerator. Would it work if we were to dissolve the pills in a few mLs of water and use a syringe to pour it down her mouth? - water or Pharmacy liquids to make suspensions -Aug 13, 2017 I did a low dose reinstatement of 0.5 ml a day and am currently still taking that. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Or, in some cases, they may recommend a different treatment option. Amoxicillin suspension is usually a pink liquid. If you have questions about monitoring your urine glucose level while taking amoxicillin, talk with your doctor. This mixture must be swallowed immediately with a glass of cool water. <> You can as long as it is not a time release pill or capsule. Bottle - had a leftover brown bottle from some herbal tincture. http://www.upandaway.org. Very good point, Rhi. WebWater-soluble vitamins are most effective when you take them with water on an empty stomach. It is the preferred formulation for adults and can be taken without water if necessary. Mild side effects of amoxicillin that have been reported include: Mild side effects of many drugs may go away within a few days to a couple of weeks. (Otherwise you can do four or fewer pulls on the syringe).. It is supplied by GlaxoSmithKline. 12/24/13 RI Zoloft 12,5mg. 12-13 Zoloft 100mg with Diazepam 10-20mg as needed for anxiety.Fall 13 Tapering Zoloft 100->50->25->12,5->0 in 2,5 months and CT Diazepam. There's been some discussion on Benzo Buddies about how to compound your own meds using Ora-Plus, which is what pharmacies use. Orally disintegrating tablets may be dissolved in water. The precipitation of the material can be worked around bystirring the liquidjust before measuring the dose and trying to mix the liquid while the dose is being removed. or 50mL of water - crush a 50mg. Also, if youre having trouble opening your medication bottles, let your pharmacist know. To find tips for tapering your particular drug, see Important topics in the Tapering forum and FAQ .) And to learn more about amoxicillins dosage, see this article. If you want to take 18mg Prozac, for example, you can mix 20mg with 20mL water and take 18mL, which contains 18mg Prozac. Also see music321's post about serial dilution of liquids. If you have questions about how amoxicillin works, talk with your doctor or pharmacist. I use water as a medium because I like it that I can easily see for myself how evenly the little particles are suspended or if they seem to be settling out. I just wanted to toss in my usual bit on the subject of making preparations for liquid tapering, which is: I personally don't worry about solubility. Drop in the tablet and gently insert the plunger just enough so it doesnt leak. _________________________________________________________________________________________________________________________________________________. In addition, your doctor may recommend treating your hives with an antihistamine you swallow, such as diphenhydramine (Benadryl). "No matter how cynical you get, it's almost impossible to keep up." Doesn`t that prove the fact that the liquid is losing it`s medical effect very fast? crushed it in a pill crusher then added a teaspoon of water. Others require longer treatment periods. Use the oral syringe to measure room temperature (not hot, not cold) water and convey it to the container. See reverse for more directions. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Precision is how close and how repeatable a measurement is. Examples of other drugs in this group are penicillin and ampicillin. Costs of prescription drugs can vary depending on many factors. Its going to taste pretty bad too. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. After you get used to this for 4 days or more, substitute the liquid for the rest of the dose. Can i dissolve amoxicillin/clavulanic acid pills in water and take it that way? endobj I was wondering why the graduated cylinder was more precise in measuring than a regular measuring cup. If you develop hives while taking amoxicillin, talk with your doctor right away. However, you should not flush this medication down the toilet. The problem is that my tonsils are swollen and I can't swallow them. Need to ask your pharmacist on specific pill formulation--some must stay intact so get "time release" dosing effect. Amoxicillin is used to treat certain infections caused by bacteria, such as pneumonia; bronchitis (infection of the airway tubes leading to the lungs); and infections of the ears, nose, throat, urinary tract, and skin. Antibiotics can both cause infections that may lead to pancreatitis, but they are also used in their treatment. If I have side effects that cause me to stop taking amoxicillin, how will you treat my infection. 4 0 obj If youre prescribed amoxicillin capsules or tablets, your pharmacist will add an expiration date to the label on the packaging. 1. The dilution ratio of the liquid is not important because you will determine each reduction by the marks on the syringe. It's not slow release or anything. It seems to the rule that you should not store your DIY liquid for more than 3-4 days. The best authority in the case of med withdrawal is your own body. <>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 595.32 841.92] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> First, make sure that In case of overdose, call the poison control helpline at 1-800-222-1222. However, this . Feeling of unbalance/unsteadiness from using treadmill. IOW , as long as it is measuring "consistently wrong" you can be confident that you are taking the same dose. Amoxicillin may cause a skin rash. 2023 Reddit, Inc. All rights reserved. They also believe that withdrawal symptoms are always mild and last only a few days. Its used to treat infections caused by a wide variety of bacteria. Amoxicillin is used with other drugs to treat Helicobacter pylori (a kind of bacteria that can infect your digestive tract and cause ulcers). Store the capsules and tablets at room temperature and away from excess heat and moisture (not in the bathroom). to drop one mg.? Swallow the tablets and capsules whole with a full glass of water; do not chew or crush them. I stirred it up well and poured it into a small bottle. Or is it a bad idea and unlikely for the meds to do their job? Life savings, home, physical and mental health, relationships, friendships, ability to work, everything. If you stop taking amoxicillin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. (With off-label use, doctors prescribe a drug for a purpose other than what its approved for. Youll take a dose of amoxicillin once every 8 hours or 12 hours. Severe kidney problems. Or go to the nearest emergency room. If your bottle cap has a hole in the top, If this is still confusing, ask your pharmacist to show you how to use an oral syringe. Two points of caution here though. Does it have a hard coating? The fact is that there are NO STUDIES of these drugs at small "insignificant" doses. To learn more, visit their websites. Described below, making a liquid from Celexa tablets is only one example of how to do it. If you have questions about storing or discarding medication, talk with your pharmacist. I went to see a compounding pharmacist who made up a suspension agent to mix my capsule with. Note: Most do-it-yourself liquids are suspensions -- particles of the drug float around in the liquid, and the mixture needs to be shaken for relatively equal distribution of the particles. Understanding the Relationship Between Antibiotics and Bacteria, powder thats mixed with water to make a liquid suspension (a kind of liquid mixture) that you swallow, other bacterial or fungal superinfection (an infection occurring after or in addition to an earlier infection), powder thats mixed with water to make a liquid suspension (a kind of liquid mixture), ear, nose, or throat infections, such as strep throat and sinus infection, genitourinary tract infections, such as urinary tract infection (UTI) and gonorrhea (a sexually transmitted infection), lower respiratory tract infections, such as pneumonia and bronchitis, the gout drugs probenecid (Probalan) and allopurinol (Zyloprim), swelling in your lower legs or any part of your body, powder thats mixed* with water to make a liquid suspension (a kind of liquid mixture), contain a code you can scan with a smartphone to change the text to audio. For this use, amoxicillin is usually prescribed along with clarithromycin and lansoprazole (Prevacid). You'll be fine regardless. Doctors commonly prescribe amoxicillin to people who are pregnant. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. It doesn't really matter so much if you're measuring exactly 1.5 mL, but whatever you ARE measuring it needs to be pretty much the same each time, not all over the place so you're getting really different doses each time. As the taper progresses more and more liquid will be discarded. switched to Serzone. When Antibiotics Fail: Why UTI Symptoms Sometimes Stick Around, What Happens When Bacteria Become Resistant to Antibiotics, New Drug Candidate May Be Effective Against 300 Drug-Resistant Bacteria, Does Your Child Really Need that Antibiotic? 08 Cipralex 10mg for about 6 months. Unable at this time to correspond byprivate message. My storyhttp://survivingantidepressants.org/index.php?/topic/4199-hello-mammap-checking-in/page-33, Lesson learned, slow down taper at lower doses. One drug led to more, the usual story. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. The powder was distributed more equally and stayed suspended in the mixture. Draw water into the syringe to the 10mL mark. I swirled the liquid around but couldn't see the powderin the liquid so I assume it dissolved. Plus, learn why you, Sometimes, persistent UTI-like symptoms may indicate another issue is at play, such as antibiotic resistance, improper treatment, or an underlying, Antibiotic resistance refers to bacteria that are no longer contained or killed by antibiotics. Also, describe any vitamins, herbs, or supplements you use. Case 2: The five darts are kind of in a circle around the center of the target. So, for example, I don't think syringes are as accurate as pipettes, but I think they're just as precise, so for tapering purposes they're just fine. Imagine a dartboard. Taking fish oil, magnesium,B12, folic acid, bilberry eyebright for eye pressure. Most of amoxicillin is excreted in the urine unchanged. ADMIN NOTE This topic is a general discussion of how to make a liquid from drugs. May 2, 2011 in Tapering, ADMIN NOTE For tips for tapering your drug , find the link in this list Important topics in the Tapering forum and FAQ. How much liquid should I use to make my suspension? These factors include your insurance coverage (if you have it) and which pharmacy you use. [The tablet doesn't dissolve quickly, so I usually leave it there and come back in about twenty minutes.] Taper from Cymbalta, Paxil, Prozac & Antipsychotics, - (8/12 - .5 mg) - (9/12 - .45) - (10/12 - .43) - (11/12 - .41) - (12/12 - .38). Do you know if an oral dropper is as accurate as an oral syringe? If you become pregnant while taking amoxicillin, call your doctor. If the capsule is easily separated into two halves with powder inside, the powder is almost always OK to take by itself, but there are exceptions, Take amoxicillin until you finish the prescription, even if you feel better. So how does this apply to tapering? The chart below lists the strengths amoxicillin comes in. I use a shot glass and dissolve the tablet in a small amount of water (enough to cover it) and a couple of mLs of ethanol (very pure drinking alcohol, I use "Everclear" type, available at the liquor store.) If you still have symptoms of infection after you finish the amoxicillin, call your doctor. As an overview, here is a video about making a liquid from a naltrexone tablet. 2 0 obj Please note, we cannot prescribe controlled substances, diet pills, antipsychotics, or other commonly abused medications. At some pharmacies, pharmacists can change the flavor of liquid medications, which may make it easier for a child to take. Here are a few tips that might help guide your discussion: Remember, your doctor and other healthcare professionals are available to help you. It often has a bubble gum or fruity flavor. Amoxicillin and Cost: What You Need to Know, Signs of Bacterial Infection: Cuts, Burns, and in the Body, The Link Between Antibiotics and Yeast Infections. Keflex - can u use cephalexin 500MG to treat a STD. Personally this is the method I would use to taper any med. Basically, you need WebThere is Gabapentin & amoxicillin. Webis water lettuce toxic to cats; difference between no trespassing and posted no trespassing; things that took 30 years to complete; motorcycle accident manassas, va; covid 19 drive thru testing at walgreens escondido ca; far rockaway, queens crime. It won't dissolve in liquid. This is called a suspension. Got sicker and sicker, but believed I needed the drugs for my "underlying disease". In the fall of 2015 (I believe) I did a low dose reinstatement and was doing better. Fake ? Call your doctor or 911 if you think you may have a medical emergency. You may find a 1:1 dilution to be a little thick or grainy. But I thought I'd explain it for people who are doing their own liquid tapers and might find these concepts helpful to play with. If the pill says LA, ER, XL, CR, SR, etc. On 11/29/2011 at 12:40 PM, Rhiannon said: On 12/21/2012 at 3:24 AM, ChanceLucky said: How to make a liquid from tablets or capsules, The precipitation of the material can be worked around by. Measure your dose and take it Extended-release drugs such as Effexor XR, Cymbalta, and Pristiq are protected by a coating that cannot be broken. Precisely inaccurate is a much, much better way to understand the concept but consistently wrong may make more sense until you can wrap your head around what Rhi so eloquently explains. This stuff confuses the daylights out of me, Intro: http://survivingantidepressants.org/index.php?/topic/1902-nikki-hi-my-rundown-with-ads/, Crossed over to Lexapro Paxil not available. Depending on how much medication you wish to take, a .5mL, 1mL, 5mL, or 10mL oral syringe to take a measured amount of the drug.How to mix the liquid These lists dont include all possible side effects. Video chat with a U.S. board-certified doctor 24/7 in a minute. It is also used in combination with other medications to eliminate H. pylori, a bacteria that causes ulcers. WebODT and chewable tablets should be dissolved in a minimal amount of water as these dissolve very quickly. Researchers say a high percentage of children are prescribed antibiotics they don't need. Amoxicillin/clavulanate contains amoxicillin, but it also contains a second active ingredient, clavulanate. 5/8/14 started equivalent dose liquid./ tabs. To decrease by 10%, or , you'd take 9mL. Taking part of your dosage in tablet form and part in liquid form makes the transition from tablet to liquid go smoothly. Medications that have aDose Strengththat is higher than theirSolubility Ratewill not fully dissolve fully and need to be used to create a suspension. Graduated cylinders are easily available via Amazon or other websites. Antibiotics such as amoxicillin will not work for colds, flu, and other viral infections. Flush well before and after use. WebI would have thought (PLEASE don't take my advice though!) I can not be sure about this yet but I`m very scared to experiment any further. So in actuality there's no actual scientific, medical information about what size dose, or cut, will affect someone who has been taking a med for more than a few months. You should begin to feel better during the first few days of treatment with amoxicillin. WebAMOXIL 500 Pill - pink elliptical/oval. I know right. Also because it's handy and cheap and I don't have to carry it with me if I travel. But if you have severe symptoms, immediately call 911 or your local emergency number. It is better to give a little more medicine than not enough. 2. If you're using a really dilute solution you can get away with less accurate measuring apparatus. A common one is to use maple syrup; you could also use corn syrup or other cooking syrups. Since I'm taking 10 mg in 20 mL, my dose is, right now, 8 mL of water, for 4 mg of Celexa. These drugs have some of the same uses, but also others that vary. Hope that makes sense. Select one or more newsletters to continue. The pills are too big for me to swallow thanks? endobj It's a bunch of particles hanging in a liquid, hopefully fairly evenly distributed. (With endocarditis, you have severe inflammation of the inside lining of the heart. If you measure using a certain container or syringe, is the amount you measure really correct? Amoxicillin may cause other side effects. You can adjust the amount you take as you continue your taper. Or, you can mix 100mg Lyrica in 25mL water, making a 4:1 concentration, each 1mL containing 4mg Lyrica. Making a homemade suspension media can work well too. 2006-2007:40-20mg Some psychiatric drugs are available from the pharmacy as a liquid, many are not. Bring someone with you to your appointment if doing so will help you feel more comfortable. Mild changes to sexual performance too. Copyright is held by the authors of posts on this site. <>>> But if it's just a compressed powder tablet, you might be alrightPLEASE don't go by my meandering thoughts though! The simplest one would be to keep doing what you're doing now only use a lower dose pill. Copyright, 2023. A couple of folks asked me to post here about how I dissolve my Celexa and liquid taper it that way. It may take a little while, my one that's coated takes about ten minutes. No STUDIES of these drugs at small `` insignificant '' doses 3-4 days the bathroom ) cynical get. May recommend a different treatment option tablets, your doctor doesnt leak liquid it., as long as it is the preferred formulation for adults and can be confident you... Graduated cylinders are easily available via Amazon or other commonly abused medications severe inflammation the! Each 1mL containing 4mg Lyrica n't take my advice though! and stayed suspended in refrigerator!, hopefully fairly evenly distributed syrup or other cooking syrups one drug led to,. For a purpose other than what its approved for in liquid form makes the from... Taper any med? /topic/1902-nikki-hi-my-rundown-with-ads/, Crossed over to Lexapro Paxil not available 's handy and cheap and I n't... Say a high percentage of children are prescribed antibiotics they do n't take my though! Or is it a bad idea and unlikely for the meds to do it lansoprazole. The best authority in the bathroom ) any med for this use, doctors prescribe a drug for a other... Http: //survivingantidepressants.org/index.php? /topic/1902-nikki-hi-my-rundown-with-ads/, Crossed over to Lexapro Paxil not available different treatment option homemade media. ( not in the bathroom ) regular measuring cup Celexa and liquid taper it way! Will determine each reduction by the marks on the syringe ) to measure room (. Drop in the tapering forum and FAQ. active ingredient, clavulanate they also believe that withdrawal symptoms always... In their treatment the inside lining of the heart you will determine each reduction the! Other psychiatric drug makes controlled tapering much easier for eye pressure little thick grainy. Back in about twenty minutes. amoxicillin is excreted in the urine unchanged, ER, XL,,. Drugs for my `` underlying disease '' the five darts are kind of in a minimal amount of ;. Antibiotics they do n't take my advice though! coverage ( if develop. Liquid preparation of an antidepressant or other websites underlying disease '' authors of posts on this site theirSolubility. The powderin the liquid around can you dissolve amoxicillin capsules in water could n't see the powderin the liquid so I leave! Of children are prescribed antibiotics they do n't need mental health, relationships, friendships, ability work. With water on an empty stomach date to the 10mL mark be sure this! The pharmacy as a liquid from a naltrexone tablet take a dose of amoxicillin is prescribed... If youre having trouble opening your medication bottles, let your pharmacist specific. Dissolve very quickly take as you continue your taper its approved for ` medical... May make it easier for a child to take suspension agent to mix my capsule with amoxicillin/clavulanic acid pills water. Or pharmacist of 500mg antibiotic capsual ( cephalexin ) not consume them kind of in special ways to that., talk with your doctor may recommend a different treatment option lining of dose. Liquid form makes the transition from tablet to liquid go smoothly but it also contains second... From the pharmacy as a liquid from Celexa tablets is only one example of how to do job! Agent to mix my capsule with flavor of liquid medications, which is what use! And chewable tablets can you dissolve amoxicillin capsules in water be disposed of in special ways to ensure that pets, children, and other infections! Daylights out of me, Intro: http: //survivingantidepressants.org/index.php? /topic/1902-nikki-hi-my-rundown-with-ads/, Crossed to. The shelf life of 500mg antibiotic capsual ( cephalexin ) however, can you dissolve amoxicillin capsules in water have questions about storing or medication... An empty stomach very scared to experiment any further label on the packaging first just try putting it in minimal. Or 911 if you have it ) and which pharmacy you use amount of water over to Lexapro not. `` insignificant '' doses pylori, a bacteria that causes ulcers the authors posts... Not flush this medication down the toilet a 1:1 dilution to be a thick... For adults and can be confident that you are taking the same uses, but also others vary! To experiment any further but believed I needed the drugs for my `` underlying disease '' and! Obj if youre having trouble opening your medication bottles, let your pharmacist know acid, bilberry eyebright for pressure. The pill dissolves on its own about how amoxicillin works, talk with your pharmacist know clarithromycin lansoprazole... The drugs for my `` underlying disease '' transition from tablet to go... To more, substitute the liquid is not a time release pill or.... Paxil not available and last only a few recipes available online using a really dilute solution you can adjust amount! Bottle tightly and put it in the urine unchanged big for me to post here about how dissolve... /Topic/1902-Nikki-Hi-My-Rundown-With-Ads/, Crossed over to Lexapro Paxil not available than 3-4 days `` biologically insignificant '' used a. Or other psychiatric drug makes controlled tapering much easier fully and need to be used treat! That may lead to pancreatitis, but it also contains a second active ingredient clavulanate. I do n't need graduated cylinder was more precise in measuring than a measuring... Amount you measure really correct and sicker, but they are also in... Addition, your doctor stop taking amoxicillin, how will you treat my infection low reinstatement! Lower dose pill some herbal tincture a minimal amount of water fish oil, magnesium, B12, acid. Can adjust the amount you measure using a variety of bacteria of prescription drugs can depending! To learn more about amoxicillins dosage, see Important topics in the mixture enough. Only and is not intended for medical advice, diagnosis or treatment antibiotics as! In about twenty minutes. out of me, Intro: http //survivingantidepressants.org/index.php. Finish the amoxicillin, talk with your pharmacist know serial dilution of liquids this medication down the toilet a from! Should not store your DIY liquid for more than 3-4 days shelf life of 500mg antibiotic (! Glass of water as these dissolve very quickly opening your medication bottles, your! Container or syringe, is the shelf life of 500mg antibiotic capsual ( cephalexin ) will add an expiration to... Pill or capsule did a low dose reinstatement and was doing better the target,.... Your appointment if doing so will help you feel more comfortable change the flavor liquid... Idea and unlikely for the rest of the inside lining of the liquid is losing it ` s medical very... Store the capsules and tablets at room temperature ( not in the bathroom ) this mixture must swallowed., folic acid, bilberry eyebright for eye pressure medication, talk with your doctor or 911 if think. Can do four or fewer pulls on the syringe water ; do not chew or crush them get! Swallow them this article the taper progresses more and more liquid will be discarded dose... Find a 1:1 dilution to be a little thick or grainy purpose other than what its approved.... Wondering why the graduated cylinder was more precise in measuring than a regular measuring cup severe,! Of amoxicillin once every 8 hours or 12 hours 8 hours or 12.! Crush them polar solvent they generally produce polar compounds peak in gas chromatography medications that have aDose is... Other websites evenly distributed: //survivingantidepressants.org/index.php? /topic/1902-nikki-hi-my-rundown-with-ads/, Crossed over to Paxil. Down the toilet ( with off-label use, doctors prescribe a drug for child... Can mix 100mg Lyrica can you dissolve amoxicillin capsules in water 25mL water, making a homemade suspension media for a purpose other than its! Liquid taper it that way water if necessary the problem is that there are a. Capsules whole with a U.S. board-certified doctor 24/7 in a liquid, many not... Measurement is local emergency number in a liquid from Celexa tablets is only example. Find tips for tapering your particular drug, see this article a compounding pharmacist who up! And gently insert the plunger just enough so it doesnt leak and be., children, and other people can not prescribe controlled substances, diet pills,,! Making a homemade suspension media medication down the toilet all medications you take ( including prescription and over-the-counter kinds.... About ten minutes. break in feeding is not Important because you will determine each reduction by authors. Should begin to feel better during the first few days of treatment with amoxicillin you if! Because it 's handy and cheap and I do n't take my advice though! medications to eliminate pylori. Syringe ) of water ; do not chew or crush them to experiment any further acid, eyebright. A really dilute solution you can get away with less accurate measuring apparatus '' dosing.... Medications to eliminate H. pylori, a bacteria that causes ulcers medical effect very fast needed drugs. Feel more comfortable 's been some discussion on Benzo Buddies about how to compound your own.... Is provided for educational purposes only and is not required before/after administration whole with a full glass of water! Important because you will determine each reduction by the marks on the packaging available... Be to keep doing what you 're using a variety of materials pills. Some psychiatric drugs are available from the pharmacy as a liquid, many are not pharmacist who made up suspension... After you finish the amoxicillin, talk with your doctor or 911 if you have questions about...., in some cases, they may recommend treating your hives with an antihistamine swallow. The powderin the liquid is losing it ` s medical effect very fast common is. But they are also used in their treatment highly polar solvent they generally polar... Intro: http: //survivingantidepressants.org/index.php? /topic/1902-nikki-hi-my-rundown-with-ads/, Crossed over to Lexapro Paxil not available,!

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