NSAIDs decrease prostaglandin synthesis. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Either increases toxicity of the other by Other (see comment). Use Caution/Monitor.oxaprozin and tolmetin both increase serum potassium. Use Caution/Monitor.oxaprozin and parecoxib both increase serum potassium. Monitor Closely (1)oxaprozin increases effects of tolbutamide by unknown mechanism. oxaprozin, vortioxetine. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. Use Caution/Monitor. Minor/Significance Unknown. Other (see comment). Increased risk of GI ulceration. Minor (1)oxaprozin will increase the level or effect of aminohippurate sodium by acidic (anionic) drug competition for renal tubular clearance. SSRIs inhib. Minor/Significance Unknown. The pain associated with these chronic conditions is often treated with a class of medications known as nonsteroidal antiinflammatory drugs (NSAIDs). Use Caution/Monitor. Use Caution/Monitor. Comment: Concomitant administration increases risk of nephrotoxicity. oxaprozin increases and bendroflumethiazide decreases serum potassium. Increased risk of GI ulceration. irbesartan and oxaprozin both increase serum potassium. cefamandole will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Concomitant administration of NSAIDs with high dose methotrexate has been reported to elevate and prolong serum methotrexate levels, resulting in deaths from severe hematologic and GI toxicity. Warnings Monitor Closely (1)oxaprozin and ginkgo biloba both increase anticoagulation. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Increased risk of GI ulceration. Monitor Closely (1)oxaprozin decreases effects of doxazosin by pharmacodynamic antagonism. etodolac and oxaprozin both increase serum potassium. Meloxicam has active ingredients of meloxicam. Monitor Closely (1)oxaprozin decreases effects of moxisylyte by pharmacodynamic antagonism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor.Minor (1)diclofenac will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. Avoid or Use Alternate Drug. Monitor patients for symptoms of active or occult gastrointestinal bleeding. Use Caution/Monitor. Comment: Combination may increase GI bleeding, ulceration and irritation. oxaprozin and succinylcholine both increase serum potassium. NOTES: Do not share this medication with others.Lab and/or medical tests (such as blood pressure, complete blood count, kidney/liver function) may be done while you are taking this medication. There are conflicting reports from studies of either increased or decreased IOP when ophthalmic prostaglandins are coadministered with NSAIDs (either systemic or ophthalmic). Talk to your doctor if you are using marijuana (cannabis).This medicine may cause stomach bleeding. unspecified interaction mechanism. Modify Therapy/Monitor Closely. Make sure laboratory personnel and all your doctors know you use this drug. Use Caution/Monitor.Minor (1)aspirin rectal will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. oxaprozin, benazepril. Effect of interaction is not clear, use caution. Increased risk of bleeding events. Use Caution/Monitor.oxaprozin decreases effects of irbesartan by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. Use Caution/Monitor. Monitor Closely (1)oxaprozin increases and chlorthalidone decreases serum potassium. cyclopenthiazide will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)oxaprozin, lisinopril. oxaprozin and potassium citrate both increase serum potassium. oxaprozin and ginger both increase anticoagulation. Use Caution/Monitor. Use Caution/Monitor.Minor (1)oxaprozin will increase the level or effect of sulfasalazine by acidic (anionic) drug competition for renal tubular clearance. Consult your doctor for more information. oxaprozin, cortisone. oxaprozin decreases effects of eplerenone by pharmacodynamic antagonism. Interaction mainly occurs in preterm infants. Use Caution/Monitor.Minor (1)metolazone will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. By clicking send, you acknowledge that you have permission to email the recipient with this information. oxaprozin and garlic both increase anticoagulation. fish oil triglycerides will increase the level or effect of oxaprozin by anticoagulation. SNRIs were also beneficial for treating low back pain. Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor.Minor (1)cyclopenthiazide will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Monitor Closely (1)oxaprozin and agrimony both increase anticoagulation. Minor/Significance Unknown. Use Caution/Monitor. Oxaprozin is indicated for the treatment of chronic arthritis due to osteoarthritis, rheumatoid arthritis and juvenile rheumatoid arthritis. analgesic-assoc. Minor/Significance Unknown. Interrupt dosing in all patients taking NSAIDs with long elimination half-lives for at least 5d before, the day of, and 2d following pemetrexed administration. Effect of interaction is not clear, use caution. Monitor Closely (1)amiloride and oxaprozin both increase serum potassium. Interaction mainly occurs in preterm infants. The Agency for Healthcare Research and Quality (AHRQ) review focused on seven common chronic pain conditions (neuropathic pain, fibromyalgia, osteoarthritis, inflammatory arthritis, low back pain, chronic headache, and sickle cell disease) and assessed the effectiveness of common nonopioid medications on the primary outcomes of pain, function, and quality of life, as well as adverse events related to these medications. antiplatelet effects. Use Caution/Monitor. Comment: Increased risk of CNS stimulation and seizures with high doses of fluoroquinolones. Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)oxaprozin, captopril. Minor/Significance Unknown. Use Caution/Monitor. Minor (1)oxaprozin will increase the level or effect of willow bark by acidic (anionic) drug competition for renal tubular clearance. Either increases toxicity of the other by pharmacodynamic synergism. Increased risk of GI ulceration. Discuss the risks and benefits with your doctor or pharmacist.In certain conditions (such as arthritis), it may take up to 2 weeks when this drug is taken regularly before you notice the full benefits.Tell your doctor if your condition worsens. Use Caution/Monitor. Avoid or Use Alternate Drug. Daypro has active ingredients of oxaprozin. Monitor Closely (1)oxaprozin and reteplase both increase anticoagulation. Either increases levels of the other by plasma protein binding competition. oxaprozin increases levels of lithium by decreasing renal clearance. Effect of interaction is not clear, use caution. celecoxib and oxaprozin both increase serum potassium. Ibrutinib may increase the risk of hemorrhage in patients receiving antiplatelet or anticoagulant therapies and monitor for signs of bleeding. Monitor Closely (1)antithrombin alfa and oxaprozin both increase anticoagulation. Use Caution/Monitor. Either increases toxicity of the other by Other (see comment). Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Use Caution/Monitor. serotonin uptake by platelets. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor. hypertensive effects. Coadministration may result in a significant decrease in renal function. Potential for increased risk of bleeding, caution is advised. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Minor/Significance Unknown. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor. Monitor Closely (2)lornoxicam and oxaprozin both increase anticoagulation. Use Caution/Monitor. Use Caution/Monitor. Personalize this study to your gender and age (0-99+). NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.olmesartan, oxaprozin. Monitor Closely (1)oxaprozin, betrixaban. Minor/Significance Unknown. serotonin uptake by platelets. Either increases toxicity of the other by Other (see comment). oxaprozin and parecoxib both increase serum potassium. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Monitor Closely (2)diclofenac and oxaprozin both increase anticoagulation. diclofenac topical, oxaprozin. Monitor Closely (1)defibrotide increases effects of oxaprozin by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor.oxaprozin decreases effects of carvedilol by pharmacodynamic antagonism. NSAIDs decrease prostaglandin synthesis. meclofenamate and oxaprozin both increase serum potassium. Meloxicam: Piroxicam: Aleve Feldene Menadol Ponstel Anaprox DS Fenoprofen: Midol Relafen Ansaid Flurbiprofen: Mobic Saleto 200 Arthrotec Genpril Motrin Sulindac: Bayer Select Pain Relief Formula Caplets: Ibuprofen: Nabumetone: Toradol Celebrex Indomethacin: Nalfon Treximet Celecoxib: Indocin . Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor. Minor (1)cefpirome will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. oxaprozin and tenecteplase both increase anticoagulation. Minor/Significance Unknown. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. nadolol and oxaprozin both increase serum potassium. Increased risk of GI ulceration. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Contact the applicable plan If coadministration of an NSAID is necessary, closely monitor patients for toxicity, especially myelosuppression, renal toxicity, and GI toxicity. Modify Therapy/Monitor Closely. Use Caution/Monitor. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. diflunisal and oxaprozin both increase serum potassium. Minor/Significance Unknown. Use Caution/Monitor. Adjust the pralatrexate dose as needed. Use Caution/Monitor. aspirin rectal and oxaprozin both increase anticoagulation. oxaprozin decreases effects of terazosin by pharmacodynamic antagonism. Monitor Closely (2)oxaprozin decreases effects of celiprolol by pharmacodynamic antagonism. This information is not individual medical advice and does not substitute for the advice of your health care professional. Either increases toxicity of the other by pharmacodynamic synergism. If coadministration of an NSAID is necessary, closely monitor patients for toxicity, especially myelosuppression, renal toxicity, and GI toxicity. metoprolol and oxaprozin both increase serum potassium. Monitor Closely (1)oxaprozin increases levels of lithium by decreasing renal clearance. Either increases levels of the other by decreasing renal clearance. Use Caution/Monitor. Minor/Significance Unknown. Copyright(c) 2023 First Databank, Inc. This information does not assure that this product is safe, effective, or appropriate for you. Minor/Significance Unknown. Use Caution/Monitor. In patients who are elderly, volume-depleted (including those on diuretic therapy), or with compromised renal function, coadministration of NSAIDs with drugs that affect RAAS may increase the risk of renal impairment (including acute renal failure) and cause loss of antihypertensive effect. All your doctors know you use this drug monitor patients for symptoms of active or occult gastrointestinal.... With a class of medications known as nonsteroidal antiinflammatory drugs ( nsaids.! Available to researchers, health care professional of the other by plasma protein binding competition volume depleted.... ( 2 ) oxaprozin decreases effects of doxazosin by pharmacodynamic synergism of vasodilating renal prostaglandins to! 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